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Dietary supplement made ​​from lactic acid bacteria

CD#2, Dietary supplement containing lactic acid bacteria

Lactobacillus brevis CD2, the friendly bacteria

The mouth is the first organ that comes into contact with the food that you ingest and it is colonized by thousands of bacteria from many different species. The oral cavity undergoes many significant changes throughout the day and, following food intake and hygiene procedures, its acidity level (pH) and salivation process are modified constantly.
These changes involve an alteration of the microflora of the mouth, with a consequent increase of potentially pathogenic bacteria. Such bacteria may be the cause of bad breath as well as of many other disorders of the oral cavity, of the stomach and of the organism as a whole.

Lactobacillus brevis CD2 is a bacteria rich in arginine deiminase. The arginine deiminase from Lactobacillus brevis CD2 competes for arginine with inducible nitric oxide synthase (iNOS) to revert the metabolism of arginine into ammonia and citrulline, resulting in a downregulation of nitric oxide and polyamine synthesis. Nitric oxide is a mediator of inflammation and inducer of other pro-inflammatory molecules such as cytokines and metalloproteinase.

* referenza Nutrition and cancer

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What is mucositis?

Oral mucositis is one of the most frequent and serious complications that occur in the course of radiotherapy or chemotherapy treatment. The presence of ulcerations in the mouth leads to severe pain, difficulty in swallowing food and drinking, which often requires analgesic therapy and systemic interventions for enteral or parenteral nutritional support. The clinical complexity and severity of patients with mucositis frequently leads to discontinuation or dose reduction of the radio-chemotherapy treatment.

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